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Our Company

Microscope

  Who Are We?  

We are BIOTECH THERAPEUTICS, LLC

  • Biotech startup founded 2022*, based in New Haven, CT &   Estero, FL

  • Specialize in Cell Therapy, AKA MSCs and Exosome nanoparticles

  • Yale Medical School classmate Co-Founders:

    • CEO John Barchilon, MD

    • CSO Professor Phil Askenase, MD

While the startup was founded in 2022, Professor Askenase has been working on exosomes for a dozen years at the Yale School of Medicine, and Dr. Barchilon for 4 years independently.

*

Examining X-ray

We have a prospective treatment for the rescue of cognition in 
Alzheimer’s disease and the dementia of Long Covid 
based on successful murine studies

Our Team

Man Portrait

John Barchilon, MD

CEO, Founding Partner

A graduate of Dartmouth, John earned his M.D. at Yale, where (as a student) he designed, raised funding, built and developed fiberoptic endoscopic and cardiac catheters, for which he was granted a U.S. patent, subsequently licensed to Cooper Laboratories and still in use. He trained briefly in surgery at The New York Hospital-Cornell Medical Center, then served as captain and C.O. of the 309th Surgical Detachment, II Corps, USAR, then returned to Yale as a fellow and faculty instructor where he did research with Richard Gershon in immunology studying B-cells and T-cells, resulting in a discovery that helped explain the mechanism by which the HIV caused AIDS; after which he took additional training in internal medicine, and ultimately became the Corporate Medical Director for Johnson & Higgins on Wall Street. John has recruited stars: Nobel-laureate chemist Melvin Calvin, Cal Tech’s botanical tissue cloning expert James Bonner, Congressional consultant on gene-splicing Nina Fedoroff, and fuel crop expert Tim Peoples for a biomass energy project & IPO in the 1980’s of which he was CEO. He was elected to the New York Academy of Sciences. In a white paper for Presidential candidate George H. W. Bush he advised on biomass/biotechnology matters, and New York City Mayoral Candidate Joel Harnett on healthcare and patient care issues. His letter in The London Financial Times calling for US tariffs in 2012 was positively received by two presidential candidates in 2015. John has been CEO of two medical practices in Los Angeles, and a Sr. Attending Urgent Care Physician at Kaiser Permanente in Woodland Hills, Southern California. He has pursued research on Covid-19 since November of 2019.

A widower since 2015, John is the busy father of 28- year-old twins.


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Man Portrait

Phil Askenase, MD

CSO, Founding Partner

Professor of Medicine & Pathology, Rheumatology and Clinical  Immunology Section, Department of Medicine, Yale School of Medicine; 333 Cedar St, New Haven, Conn. 06510; 

Dr Askenase was brought up in Long Island, NY where he played three

sports in high school. Then on to Brown Univ in Providence, RI where he

was on the starting freshman basketball team and excelled in academics;

graduating Junior Phi Beta, Kappa and Magna Cum Laude. Then to Yale

Medical School where he wrote a thesis resulting from his experiments on

viral infection induced auto immunity. Then on to Internship and Residency

in Medicine at the Harvard Medical School Unit of the Boston City Hospital.


For subsequent military service Dr. Askenase joined the Navy and was

assigned to the NIH in Bethesda, Maryland. There he developed the solid

phase immune assay and published studies on experiments demonstrating

circulating Complement fixing immune complexes in immune glomerulo-

nephritis with Dr. Edward J, Leonard, and studied clinical autoimmune

diseases with Dr. John Decker. Thereafter, Dr Askenase won a fellowship

from The British/American Heart Foundation, going to study under Dr.

Geoffrey Asherson at the London Hospital, who was the secretary of the

British Society of Immunologists and performing early studies in mice of

standard systems previously developed in guinea pigs and rabbits. There

Dr Askenase was able to interact with many leaders in world immunology

and get new ideas about a new form of cellular immunity known as cutaneous

basophil hypersensitivity, in which there was remarkable large participation

of basophils when examined by electron microscopy techniques. On return to

Yale, now on the Medical School faculty, he worked out the first procedures for

demonstrating the basophils by ordinary techniques that allowed viewing and

quantitation more easily. This led to discovery of a previously unknown

participation of antibodies and participation in crucial responses to parasites.

Returning to mice he discovered the critical role of masts cells in cellular immunity

leading to a variety of discoveries. Along the way, working in immune tolerance

there was discovery of an enigmatic factor. With the help of Sidney Altman at

Yale and colleagues at the Rockefeller their work led to discovery of participating

exosomes delivering miRNA guided by Ig antibody light chains. This led to

use of exosomes in healing responses of mesenchymal stromal cells in a variety

of responses, culminating in strong healing of spinal cord injury, their use by the

nasal route and potential for new effective and safe treatments for Long Covid

and Alzheimer's disease.

https://www.nature.com/articles/d41586-020-01764-0

http://www.ncbi.nlm.nih.gov/pubmed/?term=askenase+p+w  

Man Portrait

Dan Goldberg, MS

COO

MS Engineering, RIA, owner of Simi Valley Investment Services

Simi Valley, CA


www.simi-investments.com<http://www.simi-investments.com/>


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Man Portrait

Jim Froelich, CPA

CFO

CEO Schwartz & Froelich, Inc

Santa Monica, CA

Man Portrait

Rob Flannery, MBA, CPA, ARM

CTO

Risk Management and CTO

Estero, FL


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Man Portrait

Ryan Harding, LLD

Legal Counsel

Akerman & Associates

Expert Intellectual Property Attorneys

Man Portrait

Mark Passler

Legal Counsel

Akerman & Associates 

Expert Intellectual Property Attorneys

Man Portrait

Weston Goldberg, MS

Assoc CTO

Software Engineering, 2023

Thousand Oaks, CA


Weston Goldberg is a Computer Science graduate of California State University, Channel Islands, with hands-on experience in IT and electronics. Based in southern California, Weston has a strong background in troubleshooting and maintaining diverse technology systems, from Windows/Linux computers to network equipment and digital projectors. With a passion for custom computer builds since the age of 15, Weston has leveraged this expertise to create tailored solutions, including two systems for CEO John Barchilon. His technical proficiency spans many programming languages, complemented by skills in system configuration and database management.

Man Portrait

Lynette Johnson

Accounting/Bookkeeping

Konabay Accounting

Our Mission

GENERAL MISSION STATEMENT

Conduct Phase 1 clinical trials of our current exosome nanoparticles as treatment 

that reduces inflammation and repopulates dead or dying tissues of damaged organs 
with new, normally functioning tissue cells rather than with the usual, nonfunctioning 
scar tissue. 

SPECIFIC MISSION STATEMENTS

Rescue cognition, memory and spatial relations in patients with Alzheimer’s 
disease and patients with Long Covid Syndrome dementias via exosome-mediated 
antiinflammation, neurogenesis and angiogenesis.

Enable quadriplegics and paraplegics to walk and run again via exosome-mediated anti-inflammation, neurogenesis and angiogenesis.
             
Restore normal cardiac function in patients with coronary artery disease (CAD) 
and congestive heart failure (CHF) via exosome-mediated antiinflammation, new 
growth of cardiomyocytes, and angiogenesis.

Improve or restore worn out, osteoarthritic joints via exosome-mediated
antiinflammation and growth of new cartilage covering by new growth of chondrocytes.

Treat erectile dysfunction by exosome-mediated local therapy restoring androgen 
and vascular integrity.

Develop a robust therapeutic pipeline by pursuing the above applications plus 
searching for new applications to treat multiple major diseases.

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